Evolving health care through personal genomics.

TitleEvolving health care through personal genomics.
Publication TypeJournal Article
Year of Publication2017
AuthorsRehm, HL
JournalNat Rev Genet
Volume18
Issue4
Pagination259-267
Date Published2017 04
ISSN1471-0064
KeywordsAdult, Delivery of Health Care, Genetic Testing, Genome, Human, Genomics, High-Throughput Nucleotide Sequencing, Humans, Precision Medicine
Abstract

With the rapid evolution of next-generation DNA sequencing technologies, the cost of sequencing a human genome has plummeted, and genomics has started to pervade health care across all stages of life - from preconception to adult medicine. Challenges to fully embracing genomics in a clinical setting remain, but some approaches are starting to overcome these barriers, such as community-driven data sharing to improve the accuracy and efficiency of applying genomics to patient care.
DOI10.1038/nrg.2016.162
Alternate JournalNat. Rev. Genet.
PubMed ID28138143
Grant ListUM1 HG008900 / HG / NHGRI NIH HHS / United States
U01 HG008676 / HG / NHGRI NIH HHS / United States
U41 HG006834 / HG / NHGRI NIH HHS / United States
U19 HD077671 / HD / NICHD NIH HHS / United States
U01 HG006500 / HG / NHGRI NIH HHS / United States