@article {54,
	title = {Copy number analysis of the low-copy repeats at the primate NPHP1 locus by array comparative genomic hybridization.},
	journal = {Genom Data},
	volume = {8},
	year = {2016},
	month = {2016 Jun},
	pages = {106-9},
	abstract = {<p>Array comparative genomic hybridization (aCGH) has been widely used to detect copy number variants (CNVs) in both research and clinical settings. A customizable aCGH platform may greatly facilitate copy number analyses in genomic regions with higher-order complexity, such as low-copy repeats (LCRs). Here we present the aCGH analyses focusing on the 45~kb LCRs [1] at the NPHP1 region with diverse copy numbers in humans. Also, the interspecies aCGH analysis comparing human and nonhuman primates revealed dynamic copy number transitions of the human 45~kb LCR orthologues during primate evolution and therefore shed light on the origin of complexity at this locus. The original aCGH data are available at GEO under GSE73962. </p>},
	issn = {2213-5960},
	doi = {10.1016/j.gdata.2016.04.008},
	author = {Yuan, Bo and Liu, Pengfei and Rogers, Jeffrey and Lupski, James R}
}
